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In cellular and animal models of steroid insensitivity mediated by oxidative stress, S-CMC restored steroid sensitivity by increasing HDAC-2 expression/activity through elevating GSH and SOD levels, reducing oxidative stress, enhancing HDAC-2 recruitment and reducing H4 acetylation in the IL-8 promoter region, and eventually alleviating inflammation and lung damage [88, 89]

To view a copy of this license, visit About this article Cite this article Xiong, Y., Wu, Y., Luo, S

A combinatorial approach to producing sterically stabilized (Stealth) immunoliposomal drugs

Increases in GSSG relative to GSH are a useful indicator of oxidative stress or disulfide stress (slund and Beckwith, 1999), and in plants can be observed in response to conditions such as ozone, pathogens, and cold, as well as deficiency in important H 2 O 2 -metabolizing enzymes such as catalase and ascorbate peroxidase (APX