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Description
The lack of effect on dopamine transmission with other types of antidepressants may be a possible cause of residual symptoms such as impaired motivation, concentration, and pleasure, even in patients who initially respond to other antidepressants

doi: 10.1007/s00441-009-0751-8
Maximum cumulative benefit develops at 3-6 months of consistent daily use
When a patient self-administers a product that was stored improperly or misdosed, the side effect profile changes entirely and not in a predictable way
