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After ingestion, MNPs can cross the gastrointestinal barrier, with smaller particles more readily entering systemic circulation via the portal vein [46]

Patients should be carefully monitored with the precise monitoring chosen tailored to the patient's presenting signs and progression, and an assessment of the likelihood and nature of possible complications (see left)

A ketogenic diet increases succinic dehydrogenase (SDH) activity and recovers age-related decrease in numeric density of SDH-positive mitochondria in cerebellar Purkinje cells of late-adult rats
