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Description
Post mortem tissue from AD patients shows higher levels of oxidized bases in the frontal, parietal and temporal lobes compared to control subjects (Wang et al., 2005), which correlates with imbalanced levels of copper, zinc and iron (Montine et al., 1998
Wei Y, Wang T, Liao L, Fan X, Chang L, Hashimoto K
Ferritin, therefore, acts as an iron buffer allowing cells to resist increased oxidative pressure
It has also been reported to inhibit S aggregation and cytotoxicity in PD animal models, promoting neuronal cell survival (Xue et al., 2017
