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Cluster analysis, visualized through a heatmap, and annotation of the top differentially regulated metabolites (Figure 5B) provided insights into the metabolic shifts
Similarly, 4-PBA strongly attenuated oxidative stress in a high-fat diet or ammonia nitrogen-induced liver injury related to its ER stress-inhibiting activity (Dong et al., 2022)
It was determined that study subjects who were consuming the combo supplement had significantly lower carbon dioxide output, respiratory exchange ratio, heart rate, and blood lactate levels when compared with the placebo group

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