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Description
Glutamine is avidly taken up by HCC cells via SLC1A5/SLC38A1 transporters, and hydrolyzed to glutamate by GLS
Two-electron oxidation pathways Oxidation of Cys by two-electron oxidants, in most cases, occurs via formation of a Cys sulfenic acid (RSOH) derivative (Reactions 26 on Scheme 1)
In triple-negative breast cancer (TNBC), cells with high SLC7A11 expression consume more Gln and are more sensitive to Gln starvation compared to other breast cancer cells
Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives
