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& Fujita, D

Parenteral Vitamin B12 is the recommended treatment and will be required for the remainder of the patients life

Existing reviews tend to fall into two categories: overly broad analyses that emphasize reactive oxygen species (ROS) biology without sufficiently addressing GSH, or highly focused discussions on chemical linkers that overlook translational relevance

The disruption of the ubiquitination of NRF2 allows the escape from the proteasomal degradation, activating the NRF2 transcriptional program (Dinkova-Kostova et al
