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The architectural organization of HepatoPac cultures has been empirically optimized to promote hepatocyte vitality and enable stable metabolic activity for weeks, rather than hours or days, the typical duration of other culture systems ( Hepatic cell lines generated from tumor tissue are widely used in ex vivo culture models due to their high proliferation capacity and stable metabolism
& Chonchol, M
PMID: 98 RuhlenRLHaubnerJTracyJKZhuWEhyaHLambersonWRet al
