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In a mouse model of sepsis-induced liver failure, the upregulation of SIRT1 indicates a potential role in safeguarding hepatocytes from ferroptosis, lessening liver damage, and enhancing the clinical prognosis for liver failure (Wang et al., 2021
This dysregulation significantly contributes to the development of diseases such as alcoholic liver disease (ALD), drug-induced liver injury (DILI), and portal hypertensive gastropathy (PHG)
Targeting ferroptosis for cancer therapy: Exploring novel strategies from its mechanisms and role in cancers
Pham, V
