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doi: 10.1016/j.bmcl.2015.07.018
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Notably, however, we obtained data indicating that the prevalence of those with low IGF-1 levels was similar (27.8%) in the subjects without diabetes, suggesting that the prevalence of those with low IGF-1 levels in the present study reflects obese subjects overall

Enzymes from the TET and JMJ family catalyse histone and DNA demethylation and they are inhibited by the accumulation succinate, the by-product of these enzymes
