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The blood-based study was performed with mixed blood samples collected from different individuals and pooled together, without consideration of sex/gender
We have shown that Set7/9 attenuates MDM2 expression and suppresses MDM2 functions under DNA damage conditions 151 (Figure 4B)
Taken together, these studies highlight the importance of NAD + /NADH ratio in the modulation of metabolic processes and subsequent T cell functions
