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Filtering these by presence of the strictly conserved C P motif ( P XXX( T / S )XX C ) required for catalytic activity reduced this number to 110, uncovering multiple subfamilies encoded by all 19 metazoan species (Table 1

CETP mice injected with either vehicle, a GIPR agonist (GIPFA-085), a GLP1R agonist (GLP-140) or both agonists presented similar results ( and proatherogenic peptides and systemic inflammation markers ICAM-1 and VCAM-1 involved in monocytes/macrophages adhesion to endothelium

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