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Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes

FIGURE 2 On the other hand, in addition to its well-known functions, PGC1, a master regulator of mitochondrial biogenesis, positively regulates mitophagy by directly inducing the expression of transcription factor EB (TFEB) that mediates lysosomal biogenesis (Settembre et al., 2011)

3(f)], further indicating an increased lipid utilization

Median PFS was significantly improved with BVd versus DVd (36.6 months vs 13.4 months
