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Interestingly, however, animals treated with the humanized antibody showed reduced regeneration [161], suggesting that mechanisms of protection were different from that seen with the rodent anti-HMGB1 treatment [159]

Stringent blood pressure management, strict glycemic control, and quitting smoking are among the preventative interventions that can decrease the onset of CKD [11]

It was demonstrated that phosphorylation at the Ser637 site stimulates Ser616 phosphorylation and that only the inhibition of downstream Ser616 phosphorylation results in mitochondrial elongation (Gonzalez et al., 2021)

Given that we know BrAC is a point of care test, operators should be aware of these limitations in accuracy and potential for erroneous readings