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[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Mishra A., Prabha P.K., Singla R., Kaur G., Sharma A.R., Joshi R., Suroy B., Medhi B

Those more likely to experience rough symptoms initially include: People with chronic inflammation or autoimmune disorders

Common causes of temporary post-injection pain include: Local inflammation: The injection itself can irritate surrounding tissues Increased joint pressure: The added fluid volume temporarily stretches the joint capsule Normal healing response: Your bodys natural reaction to any needle puncture Muscle tension: Protective guarding around the injection site According to Cleveland Clinic, this reaction typically manifests as mild pain and swelling at the injection site and resolves without intervention [3]