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The brain is especially sensitive to oxidative stress because it consumes a large amount of oxygen relative to its size and contains lipid-rich membranes that can be vulnerable to oxidation
Brain or spinal cord inflammation, such as encephalitis or meningitis, is possible
However, other groups have shown that efficient mTORC1 suppression is necessary to avoid MZB loss 39
doi: 10.1016/j.bbamcr.2019.06.004 26
