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Whereas amylin acts via the amylin receptor, a complex of CALCR and one of three receptor activity modifying proteins (RAMP13), cagrilintide binds the amylin receptor and CALCR with similar potency

Radius of gyration analysis The Rg represents the spatial distribution of the atomic positions relative to the molecular axis and is a critical parameter for assessing the structural compactness and stability of proteinligand complexes

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Pharmacol Ther 143(2):133152
