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We verified the hypothesis that CHK2 might regulate hydroxylation-dependent proteasomal degradation of HIF-1 because proline hydroxylation is a chief regulator of HIF-1 protein concentrations

The bone remodeling cycle

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Furthermore, these findings indicate that ergothioneine may not only influence metabolic changes in cognitive frailty but also potentially modulate the pathological processes of T2D through its antioxidant effects [75]
