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Elevated fibrinogen significantly increases blood viscosity in the microcirculation by increasing the stacking of red blood cells or rouleaux formation

Thus, there is a need to use standardized procedures to limit possible interferences that can increase the variability between and within subjects

GHK-CU THERAPY IN CASE OF ACUTE LUNG INJURY AND RESPIRATORY FAILURE Acute lung injury (ALI), along with its most severe form, acute respiratory distress syndrome (ARDS), is a disorder of acute inflammation and tissue damage characterized by loss of alveolar-capillary membrane integrity, excessive migration of neutrophils into the epithelium, and release of proinflammatory and cytotoxic mediators leading to lung damage, which can result, among other things, in respiratory failure