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Description

All guide RNAs were validated in mouse embryos for their efficiency of generating indels on target genomic sequence, and two gRNAs targeting intron 1 and intron 2 were selected for preparing the microinjection mix

(Encinitas), 16 , 4249

NNMT (Nicotinamide N-Methyltransferase) is a cytosolic enzyme that catalyses the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide producing 1-methylnicotinamide (1-MNA) and S-adenosyl-homocysteine (SAH) as reaction products