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A study on a Tunisian population composed of 13 PF patients and seven healthy subjects evaluated MDH levels in biopsies of lesional, perilesional, and healthy skin [104]
Mouse models have shown an increase in MT in the placenta after MT elevations in the liver have taken place, which tends to sequester Zn in the process, decreasing delivery of Zn to the fetus (52)
After this clears, the skin returns to its natural color and texture
