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In turn, the mitochondria-localized glycine cleavage system (GCS) mediates the oxidative cleavage of glycine to CO 2 and NH 3 , while the cleaved methylene group is accepted by THF and the latter is reversibly converted to 5,10-methylene-THF [39]

MIT and DIT couple to form T3, while two DIT molecules couple to form T4

10.1002/jcb.10576 99 HeX.LiuX.ZuoF.ShiH.JingJ
