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While research on the therapeutic and preventive effects of spermidine on DED conditions is limited, it remains considerable to investigate the potential of spermidine to enhance tear film stability through its impact on the lipid layer, thereby reducing excessive tear evaporation

Endocrinology (2011) 152(3):91221

doi: 10.1016/s0076-6879(85)13064-8

Relative mRNA expression of Gclm (p = 0.0026), Hmox1 , Nqo1 , and Slc7a11 (d) and representative immunohistochemistry of indicated proteins (e) in Gclc WT and Gclc KO tumors (n = 6 representative from 3 independent experiments)
