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Neuropathy scores improved in seven patients, mostly in patients with immune-mediated neuropathy, but remained unchanged or worsened in the remaining five patients (two patients dropped out due to adverse events that were considered unrelated to B12)
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We conclude that ebselen binding to Cys111 restores the dimer formation affinity of A4V SOD1 to that of the wild-type
Results agree with the assumption that the synergistic phytocompounds can induce broad-spectrum immune responses, although standardization of the active molecules remains a problem
