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doi: 10.1016/S1875-5364(14)60078-9

Because of such promising results, NAC has been used as a positive antioxidant control in several experimental models to identify other antioxidant strategies to treat emphysema and other COPD complications

In addition, impaired cholesterol efflux and sustained myelin fragment accumulation within phagocytes produces an inflammatory foamy macrophage phenotype [115] which may lose their ability to effectively phagocytose debris [116]

other allergic reactions that have been reported include erythema, skin rash (unspecified), pruritus, general malaise, and respiratory difficulty due to bronchospasm