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Description
It has not been approved for any clinical indication in humans
First proteasome inhibitor approved for multiple myeloma
doi: 10.26502/jfsnr.2642-11000021
These include: receptor blocking strategies whereby putative alpha-synuclein receptors could be blocked inhibiting alpha-synuclein spread, an alpha-synuclein reduction which will decrease the amount alpha-synuclein available for aggregation and pathway disruption, the use of small molecules in order to target alpha-synuclein aggregation, immunotherapy and the increase of alpha-synuclein degradation by increasing autophagy/lysosomal flux
