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Several factors, including cytokines, proteases, growth factors, gut microbiota, and dietary components are known to regulate intestinal TJs opening ( Intestinal epithelial cells and mononuclear phagocytes sense bacteria or their products mainly through pattern recognition receptors such as TLRs (166)

[DOI] [PubMed] [Google Scholar] Han L., Hiratake J., Kamiyama A., Sakata K

Transdifferentiation of bone-marrow derived stem cells is infrequent in organs and absent in tumor metastases

Moreover, suppression of astrocytic autophagy plasticity increases the size of -amyloid plaques and the number of hypertrophic GFAP-positive astrocytes in a mouse model of -amyloidosis 585