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Description
Research has shown that repeated freeze-thaw cycles cause aggregation through multiple mechanisms, including protein adsorption to container surfaces and pH alterations from buffer crystallization during freezing

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[19] [20] Prevention and screening [edit] If a patent foramen ovale (PFO) is suspected, an examination by echocardiography may be performed to diagnose the defect

Its status as a mitochondria encoded peptide makes it a common reference point in research on mitochondrial communication and small peptide biology
