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This was a small pilot study (6 participants) results are preliminary and require confirmation in larger trials

doi: doi: 10.1073/pnas.2101119118 [DOI] [PMC free article] [PubMed] [Google Scholar] 234.Zaccolo M, Pozzan T

Since the valinomycin synthetase Vlm shows the same genetic architecture as Ces, it is tempting to speculate that the novel mechanism of non-ribosomal peptide assembly proposed in this study is not a specificity of the cereulide synthetase but a more common logic for biosynthesis of ester bond containing NRPS products, thereby contributing to biodiversity of natural depsipeptide products

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