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A notable example of a naturally occurring N- methylated peptide is cyclosporin A, a cyclic undecapeptide with immunosuppressive properties

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demonstrated that fusion of GHBP to a GHR antagonist protein similar to B2036 significantly reduced IGF1 by 14% after a single subcutaneous injection in rabbits and may be useful for treating acromegaly

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Kidney organoids derived from hPSCs have shown great potential in high-throughput screening 36

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2013;8(11):e81162

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