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Xinjiang is one of high endemic province for CE in China

When functioning as thiol-disulfide oxidoreductases, GRXs can operate like thioredoxins in reducing disulfide bridges by forming a mixed disulfide between the catalytic cysteine of the active site (Cys A ) and the client protein

This raises the risk of conditions like diabetes, atherosclerosis, and polycystic ovarian syndrome (PCOS)

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