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Left untreated, these comedones can lead to more inflamed acne bumps, but worry not: using a product like a BHA exfoliant has the potential to speed up the process and eliminate the clogs that eventually lead to acne
Michael addition of BME to 16 generates the observed product 14 (Fig
doi: 10.1021/acs.nanolett.5b05030
Because L--glutamyl-p-nitroanilide is disadvantageous for practical use in clinical chemistry testing due to its slight solubility, L--glutamyl-3-carboxy-4-nitroanilide, an alternatively modified substrate, is instead generally favored for easier handling in clinical examinations [85]
