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Yes, for most patients particularly those with absorption issues

Ribas A, 2019, 'Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001', Annals of Oncology , 30, pp

[DOI] [PubMed] [Google Scholar] Shikanai T, Takeda T, Yamauchi H, Sano S, Tomizawa K, Yokota A, Shigeoka S

These results demonstrate that GFAP+ expression is high in untreated slice cultures for the first week of culturing and this decreases with prolonged culturing out to 6 weeks (5 weeks post-treatment)
