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However, neurotoxins and dermal fillers are very different products

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5.6 Limitations of direct administration and the rationale for delivery systems In moving from laboratory findings to clinical applications, one critical bottleneck is the limited effectiveness of direct administration of therapeutic agents such as probiotics, 6-gingerol, and vitamin D

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The consequent accumulation of misfolded proteins and aggregates impairs cellular function and contributes to age-related decline and neurodegenerative diseases such as dementia [27]

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