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Monogenic and polygenic determinants of sarcoma risk: an international genetic study

500 mcg per day of vitamin B12 (cobalamin or methylcobalamin)

The polished pipettes, having a resistance of 23 Mega, were filled with an intracellular solution (100 mM CsF, 30 mM CsCl, 10 mM HEPES, 5 mM EGTA, 4 mM NaCl, 2 mM Na 2 ATP, pH 7.2, and osmolarity of 290300 mOsm/L), and used for recordings

Among the upregulated genes are those encoding DNA repair enzymes (BRCA1, ATM), extracellular matrix proteins (COL1A1, COL3A1, ELN) and antioxidant enzymes (SOD1, SOD2, GPX)
