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Microdosing starts at doses below the lowest commercially available starting dose and is titrated slowly to achieve neuromodulatory and metabolic effects without the full appetite suppression or side effects of standard dosing

The agonists against ionotropic glutamate receptors 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX, 10 M) and aminophosphonopentanoic acid (AP-5, 50 M) were used to isolate inhibitory postsynaptic currents (IPSC)

Durrieu MC, Pallu S, Guillemot F, Bareille R, Amedee J, Baquey CH, et al

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