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reported a decrease in sialic acid and superoxide dismutase (SOD) in unstimulated whole saliva in patients with DM1, and concluded that these lower values could explain the poorer oral hygiene of these patients.16 By contrast, other studies have described greater antioxidant activity in the saliva of patients with DM1 the antioxidant markers being seen to increase in parallel to HbA1c.13,17 In our study, the salivary GSSG/GSH ratio was increased in diabetic patients at the expense of two factors: an increase in GSSG and a decrease in GSH levels

Thymohydroquinone has been shown to reduce gastric acid secretion and increase mucus production in rats with ethanolinduced gastric ulcers (Paseban et al

Typical primary antioxidants include phenolic compounds, phenolic acids and their derivatives, flavonoids, tocopherols, phospholipids, amino acids, phytic acid, ascorbic acid, sterols and pigments