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Using GPX1 and GPX2-deficient mice, a recent study has shown that loss of GPX2 resulted in a robust NFkB activation and release of IL-1beta as compared to GPX1 mice
Patients with SPS-SD (or mixed SPS syndromes) often had high GAD-Abs, accompanied by intrathecal GAD-Ab synthesis and/or oligoclonal bands, and typically responded to sustained immunotherapies
doi: 10.1089/thy.2004.14.1077 83 EmderPJJackMM
