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Al-Zoughbi W, Huang J, Paramasivan GS, Till H, Pichler M, Guertl-Lackner B, Hoefler G (2014) Tumor macroenvironment and metabolism
As OxS plays an important role in PSC activation and pancreatic fibrosis, we hypothesized that high glucose could stimulate pancreatic cells to produce excess ROS and activate PSCs, that induce pancreatic fibrosis and ultimately lead to -cell failure
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GHSR-1a undergoes receptor internalization and downregulation with repeated agonist exposure
