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Transdermal patches have actually been around for a while, so we know they work effectively
This occurs partly due to a significant reduction in the expression of LaminB1, a key protein component of the nuclear membrane [29]

Mutat Res 375:18, PMID: 9129674 Weitzman SA, Turk PW, Milkowski DH, Kozlowski K (1994) Free radical adducts induce alterations in DNA cytosine methylation

10.1126/science.1124234 Science 61 GordeviciusJ.LiP.MarshallL
