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Mechanistically, GSTZ1 depletion enhanced the activation of the Nrf2 pathway and increased the GPX4 level, thereby suppressing sorafenib-induced ferroptosis (Wang Q

Importantly, it should be noted that ALOXs is not the indispensable due to the existence of other enzymatic and nonenzymatic mechanisms for lipid peroxidation

With its ability to target oxidative stress and inflammation in the lungs, nebulized glutathione holds immense potential for optimizing respiratory health and enhancing therapeutic outcomes