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L.HaufroidV.LoriotA.GattoL.AndriesV.VereeckeL.et al (2023)

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

Mechanistic studies indicate that curcumin exerts its therapeutic effects through the complex modulation of various neuroinflammatory signaling cascades, including the nuclear factor kappa-B pathway, NLRP3 inflammasome activation, and nuclear factor erythroid 2-related factor 2-mediated antioxidant responses, while downregulating pro-inflammatory cytokines (such as interleukin-6 and tumor necrosis factor-) and upregulating anti-inflammatory mediators (such as transforming growth factor- and interleukin-10) (Zia et al., 2021
