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In a study of selfconcept, approximately 30% of children and adolescents with NF1 reported a low selfconcept for physical and sporting abilities (Barton & North, 2007)

Sibutramine, a drug no longer available on the market, was an effective weight-loss drug with metabolism-boosting effects and also acted as an appetite suppressant

In this respect, OCTN2 targeted nanoparticles have been exploited for improving paclitaxel delivery (Kou et al., 2018)

patients can resume normal activities immediately, with improvement seen over several weeks
