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They were randomly divided into three groups (three mice per group) and injected intravenously through the tail vein with free DOX/SOR, D/S@MM, and D/S@SPMM, with 5 mg DOX/kg and 1 mg SOR/kg

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Excessive accumulation of ROS leads to oxidative damage to biomolecules (such as DNA, proteins, and lipids), thereby inducing oxidative stress in cells
