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The only exception was the conventional Neuromax B12 formulation, which led to significant changes in certain renal function parameters, such as serum levels of sodium, potassium, chloride, and bicarbonate, as well as in some hematological parameters, including the relative abundance of monocytes and basophils

Horm Res 40 : 6267 Mauras N (1995) Combined recombinant human growth hormone and recombinant human insulin-like growth factor I: lack of synergy on whole body protein anabolism in normally fed subjects

All formulations exhibited PDI values of 0.300.32, indicating narrow size distribution, homogeneity, and stability [67]