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Hepatosplenomegaly due to extramedullary hematopoiesis is usually present

195 Clinical drugs, such as sorafenib, 196 sulfasalazine, 197 artemisinin, 198 and ibuprofen, 199 may induce ferroptosis in cancer cells, and ferroptosis inducers combined with temozolomide, cisplatin, haloperidol, and doxorubicin can enhance the chemotherapy effect of these drugs in the treatment of tumors

For example, V lSULT ( lapap , lpaps ) is the velocity of the sulfation reaction in the liver, which depends on the concentrations of the substrates, lapap and lpaps

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