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In cross-trial comparisons, retatrutide shows greater weight loss: 28.7% vs 22.5% at similar timepoints

In a 72-week clinical trial, those patients who took the highest dose of Zepbound (15 mg) had, on average, a weight reduction of 20.99%

Activation of transcription factors: P-DSIP can induce the expression of transcription factors such as c-Fos and CREB, transmit membrane receptor signals to the nucleus, and regulate gene expression
