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Trimethylamine n-oxide (TMAO) as a new potential therapeutic target for insulin resistance and cancer
In colorectal cancer cells, C16-carnitine can produce cytotoxic effects on them by deplete glutathione [68]
Nutrition 62, 717
Consistently, we found that depleting KG either through inhibition of wildtype IDH1 or glutamine starvation, or inhibiting KGDD activity via exogenous succinate, sensitized CCNE1-driven cells to DNA damaging agents ( Fig
