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Description
It is secreted by I-cells in the duodenal and small bowel mucosa in response to protein and fat, with its main effects on the liver, gallbladder, pancreas and, interestingly, central nervous system (CNS)
To use fat for energy it requires oxygen, so this makes sense
They can also help treat B12 deficiency
NOX4 signaling mediates cancer development and therapeutic resistance through HER3 in ovarian cancer cells
