melanotic cyanosis Peripheral in Newborns, Definition:, Peripheral cyanosis (also called acrocyanosis) is a bluish discoloration of a newborn’s hands and feet while the lips, tongue, and central body remain Congenital melanocytic naevus - Skin
Description
Persistent soreness indicates either inadequate site rotation or subcutaneous (rather than intramuscular) delivery

MC1R activation drives pigmentation, while broader receptor activity contributes to systemic effects

Erbas, H., Aydogdu, N., Usta, U., and Erten, O
What affects one patient may not affect another
